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Treating neutropenias in two rare inborn errors of metabolism, glycogen storage disease Ib and G6PC3 deficiency

25€ raised

Goal 5000 €

The neutrophils are a major form of white blood cells that kill bacteria and prevent infections. When their number is abnormally decreased, patients suffer from debilitating infections. Maria Veiga da Cunha and Emile Van Schaftingen have recently understood the mechanism that causes neutropenia (too low neutrophil number) in glycogen storage disease type Ib and in G6PC3 deficiency. This knowledge led them to propose to use of an antidiabetic agent to treat these two forms of neutropenia. This treatment indeed dramatically improved the infection problems in patients. Financial support is needed to further progress in this research. References PMID: 30626647 & 32294159

— Treating neutropenias in two rare inborn errors of metabolism, glycogen storage disease Ib and G6PC3 deficiency

The de Duve Institute is a multidisciplinary biomedical research institute hosting several research laboratories of the Faculty of Medicine of the UCLouvain, as well as the Brussels branch of the Ludwig Institute for Cancer Research.

The de Duve Institute is based on three key principles:
- priority to fundamental research and freedom of researchers,
- special attention to the medical benefits that may result from fundamental discoveries,
- multidisciplinary collaboration in an environment of skills, techniques and equipment.

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donation to "Treating neutropenias in two rare inborn errors of metabolism, glycogen storage disease Ib and G6PC3..."

25 €

Gauthier — 2 years ago

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Scientific report 2020

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Treating neutropenias in two rare inborn errors of metabolism, glycogen storage disease Ib and G6PC3 deficiency

Donation (1)

What does "fundamental research" means?

Read more about the research of the de Duve Institute

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